Polysorbate 20 Degradation in Biopharmaceutical Formulations: Quantification of Free Fatty Acids, Characterization of Particulates, and Insights into the Degradation Mechanism

Full article: Prediction of long-term polysorbate degradation according to short-term degradation kinetics

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Polysorbate, the Good, the Bad and the Ugly American Pharmaceutical Review - The Review of American Pharmaceutical Business & Technology

Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation

Formulation mitigations for particle formation induced by enzymatic

Residual Host Cell Protein Promotes Polysorbate 20 Degradation in a Sulfatase Drug Product Leading to Free Fatty Acid Particles - Journal of Pharmaceutical Sciences

Full article: Prediction of long-term polysorbate degradation according to short-term degradation kinetics

Considerations for the Use of Polysorbates in Biopharmaceuticals

Understanding Particle Formation: Solubility of Free Fatty Acids as Polysorbate 20 Degradation Byproducts in Therapeutic Monoclonal Antibody Formulations